Advanced OBGYN

Abstract. Research conducted in recent years provides more and more evidence that diet can have a significant impact on male fertility. The aim of the study was to analyze the relationship between diet, energy balance and fertility in men. A comprehensive literature search of published studies in various languages, was carried out in electronic databases. The direct analysis included 96 works published between 2008 and 2018, including 12 randomized controlled trials and 23 systematic reviews and meta-analyses. A strong adherence to a healthy dietary pattern is positively correlated with total sperm count, progressive motility and total motile sperm count (all p < 0.05). However, attention is drawn to the fact that foods that are considered “healthy” can sometimes contain a significant amount of pollution, which negatively affect the semen parameters. An adequate intake of antioxidants or their supplementation have been quite effective in the prevention and treatment of male infertility. The improvement of pregnancy rate after antioxidant therapy ranged in various studies from 11% to 41%. An important problem, however, may be choosing the right dose of the supplement or finding an appropriate combination of antioxidants that may be more effective than any single antioxidant. The normalization of men's body weight is beneficial for the quality of sperm and the concentration of male reproductive hormones. Further, long-term studies require the assessment of the impact of drastic weight loss after bariatric surgery on male fertility.

Inclusion

The new prevalence of infertility certainly people out of reproductive age brackets, according to some provide, off 8% in order to 25% [1–3]. Men infertility ‘s the only factor in sterility inside 20–30% out of times and you can the one thing contributing to infertility inside the fifty% of all the sterility instances . New investigations of male potency constantly boasts medical examination and you can evaluation into the source opinions of your own pursuing the semen details: regularity, complete sperm fertility, quantity, motility and you can morphology (Dining table step 1) . Reduced sperm count and you will/otherwise high quality exists inside the 90% off couples having virility problems . In the assessment out of fertility, the new density out of men reproductive hormonal are also analyzed. Recently, the fresh molecular composition from jizz cells, reviewed of the researching the degree of DNA fragmentation otherwise oxidative worry could have been even more taken into consideration. Multiple education make use of the DNA fragmentation list (DFI) given that indicative of being pregnant triumph. Predicated on Evenson and you may Wixon, DFI selections out-of three to five% into the healthy men, when you are a good DFI from https://datingranking.net/escort-directory/buffalo/ ? 30% is actually associated with smaller fertility . Already laid out genetic activities, together with each other chromosomal aberrations and monogenic change, account for just about ten–15% out-of cases of male sterility . The reason to own virility troubles can also be environment affairs. The goal of the study was to become familiar with the partnership between eating plan, times balance and you may virility prices inside boys.

Strategy regarding literature look

A comprehensive literature search of published studies in various languages, was carried out in electronic databases, including: PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Database of Systematic Review and Google Scholar. Randomized controlled trials, observational and qualitative studies published between 2008 and 2018 (up to and including March) were included. The following keywords related to male infertility, diet, nutrients and their combinations (made by applying operators AND and OR) were used in the search: ‘male infertility’, ‘sperm quality’, ‘idiopathic oligozoospermia’, ‘astenoazospermia’, ‘oligoastenoteratozoospermia’, ‘sperm DNA damage’, ‘nutritional status’, ‘BMI’, ‘obesity’, ‘diet’, ‘nutrition’, dietary pattern’, ‘food’, ‘nutrient’, ‘fatty acids’, ‘antioxidant’, ‘supplementation’, ‘vitamin C’, ‘vitamin E’,’ vitamin A’, ‘folate’, ‘zinc’, ‘selenium’, ‘L-carnitine’, ‘glutathione’, ‘coenzyme Q₁₀‘, ‘N-acetylcysteine’, ‘lycopene’. Reference lists of studies extracted from the primary electronic search were used to identify additional relevant studies.